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Genetically attenuated parasites

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Malaria,Falciparum Trial in Leiden (biological, drug, other)

Not yet recruiting
  • Malaria,Falciparum
  • GA2
  • +4 more
  • Leiden, Netherlands
    Leiden University Medical Center
Jul 18, 2022

Malaria,Falciparum, Plasmodium Falciparum, Plasmodium Berghei Trial in Nijmegen, Rotterdam (Pb(PfCS@UIS4)-infected mosquitoes,

Completed
Has Results
  • Malaria,Falciparum
  • +3 more
  • Pb(PfCS@UIS4)-infected mosquitoes
  • Challenge infection P. falciparum
  • Nijmegen, Gelderland, Netherlands
  • +1 more
Feb 23, 2022

Plasmodium Falciparum Infection Trial in Seattle (Genetically-attenuated p52-/p36-/sap1- Plasmodium falciparum parasite (GAP3KO)

Completed
  • Plasmodium Falciparum Infection
  • Genetically-attenuated p52-/p36-/sap1- Plasmodium falciparum parasite (GAP3KO) strain
  • Malaria challenge
  • Seattle, Washington
    Kaiser Permanente Washington Health Research Institute - Vaccine
Sep 19, 2019

Malaria Trial in Silver Spring (p52-/p36- GAP Vaccine, p52-p36- GAP Vaccine)

Terminated
Has Results
  • Malaria
  • p52-/p36- GAP Vaccine
  • p52-p36- GAP Vaccine
  • Silver Spring, Maryland
    Walter Reed Army Institute of Research
Oct 4, 2019

Malaria Trial in Leiden, Nijmegen (PfSPZ-GA1 Vaccine, PfSPZ Vaccine, Normal Saline)

Completed
  • Malaria
  • PfSPZ-GA1 Vaccine
  • +3 more
  • Leiden, Netherlands
  • +1 more
Mar 4, 2019

Metastatic Pancreatic Cancer Trial in Montreal (Salmonella-IL2, FOLFIRINOX Alone (Historical Controls), Gemcitabine/Abraxane

Recruiting
  • Metastatic Pancreatic Cancer
  • Montreal, Quebec, Canada
    Segal Cancer Centre/ Mortimer B. Davis-Jewish General Hosptial
May 3, 2022

GSK's Phase IIb Malaria Vaccine Trial Entitled "Efficacy, Safety

Active, not recruiting
  • Malaria
    • Kumasi, Ghana
    • +1 more
    Jun 23, 2022

    Advanced Solid Tumor Trial in Switzerland, United Kingdom (Pembrolizumab+T3P-Y058-739, T3P-Y058-739 (IV), T3P-Y058-739 (IT))

    Recruiting
    • Advanced Solid Tumor
    • Lausanne, Switzerland
    • +4 more
    Jun 22, 2022

    Gastroenteritis Trial in China (GSK's liquid oral live attenuated HRV, PCV-free liquid formulation of GSK's oral live attenuated

    Recruiting
    • Gastroenteritis
    • GSK's liquid oral live attenuated HRV
    • PCV-free liquid formulation of GSK's oral live attenuated HRV
    • Chengdu, Sichuan, China
    • +7 more
    Sep 7, 2023

    Liver Cirrhosis Trial in Sohag (stool analysis)

    Not yet recruiting
    • Liver Cirrhosis
    • stool analysis
    • Sohag, Egypt
      Sohag university hospital
    May 3, 2023

    Malaria Trial in Lambaréné (PfSPZ Vaccine, Normal Saline)

    Completed
    • Malaria
    • PfSPZ Vaccine
    • Normal Saline
    • Lambaréné, Moyen-Ogooué, Gabon
      Centre de Recherches Médicales de Lambaréné (CERMEL)
    Oct 6, 2021

    Varicella Zoster Virus Infection Trial (MG1111)

    Not yet recruiting
    • Varicella Zoster Virus Infection
    • MG1111
    • (no location specified)
    Dec 16, 2022

    Uncomplicated Plasmodium Falciparum Malaria Trial (Artemether-Lumefantrine-Amodiaquine (ALAQ), Artemether-Lumefantrine (AL),

    Not yet recruiting
    • Uncomplicated Plasmodium Falciparum Malaria
    • Artemether-Lumefantrine-Amodiaquine (ALAQ)
    • +2 more
    • (no location specified)
    Jul 20, 2023

    SARS-CoV-2 Infection Trial in Baltimore (B/HPIV3/S-6P)

    Recruiting
    • SARS-CoV-2 Infection
    • B/HPIV3/S-6P
    • Baltimore, Maryland
      Johns Hopkins Bloomberg School of Public Health
    Aug 30, 2023

    Adenovirus Infection, BK Virus Infection, Cytomegaloviral Infection Trial in Houston (Virus-specific Cytotoxic T-lymphocytes)

    Recruiting
    • Adenovirus Infection
    • +6 more
    • Virus-specific Cytotoxic T-lymphocytes
    • Houston, Texas
      M D Anderson Cancer Center
    Jan 6, 2023

    Lung Cancer, Small-cell Lung Cancer, Non Small Cell Lung Cancer Trial in Philadelphia (Carboplatin, Pemetrexed, Paclitaxel)

    Recruiting
    • Lung Cancer
    • +2 more
    • Philadelphia, Pennsylvania
      Fox Chase Cancer Center
    Mar 24, 2023

    Varicella Trial in Xuzhou (Investigational live attenuated varicella vaccine (lot 1), Investigational live attenuated varicella

    Not yet recruiting
    • Varicella
    • Investigational live attenuated varicella vaccine (lot 1)
    • +2 more
    • Xuzhou, Jiangsu, China
      Xinyi Center for Disease Control and Prevention
    Apr 20, 2023

    Malaria,Falciparum, Malaria in Pregnancy, Malaria in Childbirth Trial in Kinshasa, Eldoret (Malaria High-Sensitivity Rapid

    Not yet recruiting
    • Malaria,Falciparum
    • +8 more
    • Malaria High-Sensitivity Rapid Diagnostic Test (HS-RDT)
    • Artemether-Lumefantrine 20 Mg-120 Mg Oral Tablet
    • Kinshasa, Congo, The Democratic Republic of the
    • +1 more
    Feb 24, 2023

    NSCLC, Head and Neck Squamous Cell Carcinoma, Colorectal Carcinoma Trial in Duarte (Autologous, engineered T Cells targeting

    Not yet recruiting
    • Non-small Cell Lung Cancer
    • +5 more
    • Autologous, engineered T Cells targeting TP53 R175H
    • Duarte, California
      City of Hope
    May 17, 2023

    Varicella Trial in Xuzhou (Investigational live attenuated varicella vaccine, Placebo of live attenuated varicella vaccine)

    Recruiting
    • Varicella
    • Investigational live attenuated varicella vaccine
    • Placebo of live attenuated varicella vaccine
    • Xuzhou, Jiangsu, China
      Pei County Center for Disease Control and Prevention
    Jan 18, 2023

    Bacterial Growth, Novel Influenza A (H1N1) Trial in Jilin (A novel electrolyzed water spray reduces numbers of bacteria E-coli

    Recruiting
    • Bacterial Growth
    • Novel Influenza A (H1N1)
    • A novel electrolyzed water spray reduces numbers of bacteria E-coli and an attenuated human flu virus on human hands
    • Jilin, Changchun, China
      Changchun Jiahe Surgery Hospital
    Apr 1, 2023

    Malaria Trial in Bagamoyo (SumayaVac-1(SUM-101), Verorab, CHMI)

    Not yet recruiting
    • Malaria
    • SumayaVac-1(SUM-101)
    • +2 more
    • Bagamoyo, Tanzania
      Ifakara Health Institute
    Dec 1, 2022

    Severe Malaria Trial in Worldwide (KAE609, IV Artesunate, Coartem)

    Recruiting
    • Severe Malaria
    • Kinsasha, Democratic Republic Of Congo, Congo
    • +6 more
    Sep 23, 2022

    ß-thalassemia Trial in Shanghai (BD211)

    Not yet recruiting
    • β-thalassemia
    • BD211
    • Shanghai, China
      Shanghai Ruijin Hospital
    Mar 16, 2023

    Respiratory Syncytial Virus Infection Trial in Carolina, Guayama, San Juan (RSVt Vaccine, Control Group)

    Recruiting
    • Respiratory Syncytial Virus Infection
    • RSVt Vaccine
    • Control Group
    • Carolina, Puerto Rico
    • +2 more
    Feb 2, 2023